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Impotence, also known as erectile dysfunction, is a condition that affects a man's ability to achieve or maintain an erection during sexual activity. It can have a significant impact on a man's self-esteem, relationships, and overall quality of life. , There are many factors that can contribute to impotence, including physical and psychological causes. Physical causes may include health conditions such as diabetes, high blood pressure, and heart disease, as well as medications, smoking, and alcohol use.